Isotopically Labeled Compounds
Medchemexpress LLC Erythromycin-d3 | 959119-26-7 | 95.0% | 1 MG
Erythromycin-d3 is a deuterium-labeled macrolide antibiotic produced by the actinomycete Streptomyces erythreus. It exhibits broad-spectrum antimicrobial activity by binding to bacterial 50S ribosomal subunits, thereby inhibiting RNA-dependent protein synthesis. Beyond its antibiotic properties, Erythromycin also demonstrates antitumor and neuroprotective effects in various research areas.
- Can be utilized as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Adenosine-1′-13C | 201996-55-6 | 96.3% | 1 MG
Adenosine-1′-13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology and is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation
- Has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Cytidine-13C (Cytosine β-D-riboside-13C) | 201996-57-8 | 99.0% | 100 MG
Cytidine-13C is a 13C labeled pyrimidine nucleoside that acts as a component of RNA. It is a precursor of uridine and controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism and catecholamine. This compound is intended for research use only and is not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Taurine-13C2 | 70155-54-3 | MFCD01075566 | 99.9% | 5 MG
Taurine-13C2 is a 13C-labeled form of Taurine, a sulfur-containing amino acid and organic osmolyte. It plays a role in cell volume regulation, serves as a substrate for bile salt formation, and modulates intracellular free calcium concentration. Taurine has also been shown to activate autophagy in adipocytes.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Molecular weight: 127.13
- Isotopic purity: ≥99 atom % 13C
- Assay: ≥98% (CP)
- Mass shift: M+2
- Physical form: solid
- Suitable for bio NMR and mass spectrometry (MS) techniques
- Melting point: >300 °C
Medchemexpress LLC D-Glucose-d12-1 | 89798-27-6 | 99.4% | 100 MG
D-Glucose-d12-1 is a deuterium-labeled D-Glucose, which is a monosaccharide essential for general metabolism and acts as a critical signaling molecule in cellular metabolic status and stress response. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Bromhexine-d3 hydrochloride | 611-75-6 | 99.0% | 1 MG
Bromhexine-d3 (hydrochloride) is a deuterium-labeled Bromhexine (hydrochloride) that functions as a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. It holds potential for preventing and managing SARS-CoV-2 infection and also acts as an autophagy agonist. Additionally, Bromhexine hydrochloride serves as a mucolytic cough suppressant, suggesting its utility in various respiratory conditions. This product is intended for research use only.
- Deuterium labeled Bromhexine (hydrochloride)
- Potent and specific TMPRSS2 protease inhibitor
- Can prevent and manage SARS-CoV-2 infection
- Autophagy agonist
- Mucolytic cough suppressant
- Used as a tracer or internal standard for quantitative analysis
Medchemexpress LLC D-Glucose-13C2 | 201741-04-0 | 98.0% | 100 MG
D-Glucose-13C2 is the 13C labeled D-Glucose, a critical monosaccharide for general metabolism and a signaling molecule related to cellular metabolic status and stress response. This compound can be used as a tracer or an internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC D-Glucose-d12-1 | 89798-27-6 | 99.4% | 50 MG
D-Glucose-d12-1 is a deuterium-labeled D-Glucose. It is a monosaccharide, a crucial carbohydrate in biology, a carbohydrate sweetener, and a vital component of general metabolism. It also serves as a critical signaling molecule related to cellular metabolic status and biotic and abiotic stress responses.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development.
- Deuteration can potentially affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 9-octadecenoic acid (9z)-, 2,3-dihydroxypropyl-1,1,2,3,3-d5 ester | 565183-24-6 | 99.9% | 10 MG
Monoolein-d5 is a deuterium labeled monoolein with high purity, making it suitable for research applications requiring isotopic labeling. Its structure has been confirmed by 1H NMR and mass spectrometry.
- Purity of 99.9% (HPLC)
- Isotopic enrichment of 99.9%
- Structure confirmed by 1H NMR and MS
- Store at 4°C, sealed, away from moisture and light
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Risdiplam-d4 | 1825352-65-5 | 98.9% | 405.49 | 100 MG
Risdiplam-d4 is a deuterium-labeled version of Risdiplam. Risdiplam (RG7916) is an orally administered SMN2 pre-mRNA splicing modifier that is distributed both centrally and peripherally, and it works by increasing survival motor neuron (SMN) protein levels.
- This compound can be used as a tracer.
- It can serve as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Istradefylline-13C,d3 | 2749234-46-4 | 98.3% | 388.44 | 50 MG
Istradefylline-13C,d3 is the 13C- and deuterium labeled Istradefylline. It is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Sigma Aldrich Fine Chemicals Biosciences Aldicarb-(N-methyl-13C,d3 carbamoyl-13C) >=98 atom %, >=98% (CP) | 1261170-75-5 | MFCD17677362 | 25MG
Aldicarb-(N-methyl-13C,d3 carbamoyl-13C) >=98 atom %, >=98% (CP) | Purity: >=98% (CP) | Mol Wt: 195.27 | 1261170-75-5 | MFCD17677362 | 25MG
Medchemexpress LLC (±)-Linalool-d3 (vinyl-d3) | 1216673-02-7 | MFCD11109274 | 95.2% | 157.27 g/mol | C10H15D3O | 10 MG
Linalool-d3 is a deuterium-labeled analogue of the natural monoterpene linalool, supplied as a stable-isotope reference standard for analytical and research use. It is intended for use as an internal standard and for isotope-tracing experiments in GC-MS or LC-MS workflows, with documented purity, molecular weight, and solubility information available in the manufacturer datasheet and certificates.
- Deuterium-labeled internal standard for analytical assays.
- High purity suitable for quantitation and method validation.
- Soluble in common organic solvents, including DMSO.
- Provided in a small, laboratory-scale vial for trace-level work.
- Recommended storage conditions to preserve stability.
Medchemexpress LLC Pyrrolidin-3-ol-d5 | 1219805-52-3 | 92.15 g/mol | C4H4D5NO | 5 MG
Pyrrolidin-3-ol-d5 is a deuterium-labeled analogue of pyrrolidin-3-ol supplied as a small milligram vial for use as a tracer and internal standard in quantitative analysis by NMR, GC-MS, and LC-MS.
- Deuterium-labeled tracer and internal standard.
- Used for quantitative analysis by NMR, GC-MS, and LC-MS.
- Offered in small milligram pack sizes for analytical workflows.
- Storage: pure form -20°C; in solvent -80°C (short term) or -20°C.